GENETICS

CONTENTS: 1. Genetics: Definitions, History and Scope; 2. Mendel’s Laws of Inheritance; 3. Lethality and
Interaction of Genes; 4. Quantitative Genetics: Multiple Factor Hypothesis; 5. Multiple Alleles and Isoalleles : (Classical Concept of Allelomorphism); 6. Physical Basis of Heredity: 1. The Chromosome Theory of Inheritance; 7. Physical Basis of Heredity : 2. The Nucleus and the Chromosome; 8. Physical Basis of Heredity : 3. Cell Division (Mitosis and Meiosis); 9. The Cell Division Cycle: Genetics and Molecular Basis; 10. Linkage and Crossing Over in Diploid Organisms (Higher Eukaryotes); 11. Tetrad Analysis, Mitotic Recombination and Gene Conversion in Haploid Organisms : (Fungi and Single Celled Algae); 12. Genetics of Cell Division, Sexuality and Recombination in Bacteria and Viruses; 13. Molecular Basis of Recombination; 14. Recombination and Resolution of Gene Structure: (A Modified Concept of Allelomorphism); 15. Accessory Genetic Elements: Plasmids, Transposons and Retroelements; 16. Sex-Linked, Sex-Influenced and Sex-Limited Traits; (Including Sex-Biased Inheritance); 17. Genetics of Sex Determination, Sex Differentiation and Dosage Compensation; 18. Maternal Effects and Cytoplasmic Inheritance; 19. Structural Changes in Chromosomes; 20. Numerical Changes in Chromosomes; 21. Mutations: 1. Morphological Level (Including Lethal Mutations); 22. Mutations: 2. Biochemical Level (Biochemical and Microbial Genetics); 23. Mutations: 3. Molecular Mechanism and Use in Functional Genomics; 24. Human Genetics and Genomics; 25. Chemistry of the Gene: 1. Nucleic Acids and Their Structure; 26. Chemistry of the Gene: 2. Replication and Modification of DNA; 27. DNA Damage and DNA Repair; 28. Organization of Genetic Material: 1. Genome Size, C-Value Paradox and Repetitive DNA Sequences; 29. Organisation of Genetic Material: 2. Packaging of DNA as Nucleosomes in Eukaryotes; 30. Organization of Genetic Material: 3. Mitochondrial, Chloroplast and Apicoplast Genomes; 31. Organization of Genetic Material: 4. Split Genes, Overlapping Genes, Pseudogenes, Retrogenes and Cryptic Genes; 32. Dynamic RNA: Ribozymes, Small/Long ncRNAs and RNA World; 33. The Genetic Code; 34. Transcription in Prokaryotes and Eukaryotes; 35. RNA Processing: (Decay, Splicing, Editing and Repair of RNA); 36. Expression of Gene and Protein Synthesis: 3. Molecular Machines for Translation of mRNA (Ribosome, tRNA and aaRS); 37. Expression of Gene and Protein Synthesis: 4. Protein Structure and Translation of mRNA in Prokaryotes and Eukaryotes; 38. Protein Modification, Folding, Translocation and Degradation; 39. Operon Circuits in Bacteria and Other Prokaryotes; 40. Regulation of Gene Expression: 2. Regulation Cascades in Bacteriophages; 41. Regulation of Gene Expression: 3. A Variety of Mechanisms in Eukaryotes; 42. Regulation of Gene Expression: 4. Chromatin Remodeling and Cellular Memory; 43. Cell Receptors and Signal Transduction; 44. Genes in Development; 45. Epigenetics and Epigenomics; 46. Genetic Engineering and Biotechnology : 1. Recombinant DNA, Cloning, PCR and Microarrays; 47. DNA-Based Molecular Markers; 48. Isolation, Synthesis and Sequencing of Genes/Genomes: (Including ‘Synthetic Genomics’); 49. Genetic Engineering and Biotechnology: 4. Gene Transfer Methods and Transgenic Organisms; 50. Multigene Families in Eukaryotes; 51. Omics Technologies: Genomics, Transcriptomics, Proteomics and Metabolomics (Including Single Cell Omics); 52. Genetics of Cancer: Oncogenes, Tumour Suppressor Genes, Tumour Viruses and Oncogenesis; 53. Population and Evolutionary Genetics; 54. Genetics of Inbreeding Depression and Heterosis;–References;–Author Index; –Subject Index.